Found 46 matching trials
Dexamethasone Solution for the Treatment of Oral Lichen Planus PHASE2 The objective of this single center, 4-week, open label randomized, phase I...
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Brigham and Women's Hospital
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Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009) PHASE3 The purpose of this study is to evaluate sacituzumab tirumotecan versus pem...
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Active Not Recruiting
Location
Kaiser Permanente - Oakland ( Site 0054)
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A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015) PHASE3 This study will compare how safe and effective sacituzumab tirumotecan is v...
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Active Not Recruiting
Location
Banner MD Anderson Cancer Center ( Site 0119)
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Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005) PHASE3 Researchers are looking for new ways to treat people with endometrial cance...
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Active Not Recruiting
Location
USA Mitchell Cancer Institute ( Site 4142)
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Dexamethasone to Prevent Oral Chronic Graft-versus-Host Disease PHASE2 This study will determine if a dexamethasone mouth rinse can reduce the ris...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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Preventing Dato-DXd Associated Stomatitis With Dexamethasone Mouthwash, TROPION-DM PHASE2 TROPION-DM/BrUOG-431 is a prospective, , phase 2 trial with two non-compara...
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Rhode Island and the Miriam Hospitals (Brown University Health)
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Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06) PHASE1 Researchers are looking for new ways to treat esophageal squamous cell carc...
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UPMC Hillman Cancer Center ( Site 1904)
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A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer) PHASE3 This Phase III, randomized, open-label, multicenter study will evaluate the...
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Active Not Recruiting
Location
Alaska Oncology & Hematology, LLC
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Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01) PHASE2 The main goals are after treatment given before surgery, to measure the num...
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Southern Cancer Center (SCC) ( Site 8004)
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A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032) PHASE3 Researchers are looking for new ways to treat types of breast cancer that a...
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Banner MD Anderson Cancer Center ( Site 0066)
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